A new study discovered a previously unknown mechanism by which dopamine drives mitochondrial energy production.
Northwestern Medicine scientists have discovered that mutations in the largest genetic contributor to ALS leads to the dysfunction and eventual degeneration of certain specialized subtypes in the brain. The findings may lead to development of novel therapeutic interventions for the disease.
Northwestern has formed the Center for Translational Pain Research, which aims to advance basic and clinical science in the hopes of developing non-addictive treatments for chronic pain.
Joel Voss, PhD, and John Disterhoft, PhD, have received a $6.3 million grant from the NIH as part of the BRAIN Initiative.
Talia Lerner, PhD, has received the NIH Director's New Innovator Award, an early-career grant supporting projects in the biomedical, behavioral or social sciences.
A molecule drastically reduced toxic proteins in human neuron cells with Huntington’s disease, representing a potential therapy for the deadly degenerative disease, according to a new study.
Northwestern Medicine scientists have discovered that the protein FMRP — the loss of which leads to Fragile X syndrome — is a novel reader of RNA methylation.
A new study published in Developmental Cell discovered a link between a previously unknown mitochondrial process and Charcot-Marie-Tooth disease Type 2, a genetic neuropathy.
With advances in technology and genetics, Feinberg and Northwestern investigators are conducting basic science research to understand just how the retina works in concert with the brain.
A recent study revealed how sensory processing centers communicate with one another within brain, with implications for neurodegenerative disease.
Northwestern Medicine scientists have mapped a brain circuit that sends information from the hippocampus and thalamus to the retrosplenial cortex, an area of the brain involved in memory formation.
According to a recent study, a novel nanoparticle-based drug repaired neurons and improved microvasculature in a mouse model of spinocerebellar ataxia 1, a degenerative disease that affects the cerebellum.
Abnormal activation of a small population of neurons may contribute to motor learning and motor function deficits in patients with Parkinson’s disease, according to a recent study.
Northwestern Medicine scientists have discovered that amacrine cells produce nitric oxide, a neuromodulator that regulates blood dilation, in a recently published study.
Northwestern Medicine scientists have discovered a mechanism for rapid, fine adjustments in motor plans, according to a recent study.
In a study published in Nature, Northwestern Medicine scientists have demonstrated that a gene is critical for the development of the ear’s outer hair cells, which has important implications for hearing loss treatments.
Scientists have shown they can predict which chronic pain patients will respond to a placebo pill based on brain anatomy and psychological characteristics.
In a study published in Nature Neuroscience, Northwestern Medicine scientists demonstrated that subtypes of dopamine neurons have distinct projection patterns.
Treating mice with isradipine, a calcium channel blocker, prevented formation of toxic compounds that can cause Parkinson’s disease symptoms, according to a recent Northwestern Medicine study.
Northwestern Medicine scientists used an innovative technique to measure electrical activity in ALS neurons, finding changes in excitability that indicated disease, according to a study published in Stem Cell Reports.
Feinberg met its goal of raising $10 million for the newly renamed Mesulam Cognitive Neurology and Alzheimer’s Disease Center, naming the Center after its director, M. Marsel Mesulam, MD.
Northwestern scientists restored chemical balance to certain brain cells in mouse models, reversing mechanisms that may be responsible for sensory hypersensitivity in patients with autism.
The newly-launched Center for Autism and Neurodevelopment is a translational science hub that aims to investigate the neurobiology of autism and facilitate the development of new treatments.
Northwestern Medicine scientists have uncovered how DNA methylation triggers stem cells to transform into more specialized neuronal cells.