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The Department of Physiology at Northwestern University Feinberg School of Medicine holds events for faculty, residents, and fellows. See details on the individual events via the entries below.
The department of Physiology welcomes Min Cho, Ph.D.
The department of Physiology welcomes Kathleen Cullen, Ph.D.
The department of Physiology welcomes Nicola Grissom, Ph.D.
Focus of Work: Retina, synaptic transmission, glutamate, vision
The department of Physiology welcomes Chenghua Gu, Ph.D.
The department of Physiology welcomes Lisa Monteggia, Ph.D.
Clinical studies have demonstrated that a single subpsychotomimetic dose of ketamine, an N-methyl-D-aspartate (NMDA) receptor antagonist, produces rapid antidepressant responses in patients with major depressive disorder. Data will be presented showing that ketamine mediated blockade of NMDA receptors at rest targets a specific signaling cascade that involves deactivation of eukaryotic elongation factor 2 (eEF2) kinase, resulting in reduced eEF2 phosphorylation and desuppression of rapid dendritic protein translation, including BDNF, which then contributes to synaptic plasticity mechanisms. These findings identify critical determinants of how blocking spontaneous neurotransmission impacts synaptic plasticity with implications for ketamine mediated antidepressant responses.
The department of Physiology welcomes Amanda Law, Ph.D.
Focus of Work: Research in my lab centers on signal transduction networks that regulate the structural and functional plasticity of excitatory synapses.
The department of Physiology welcomes Jeanne Paz, Ph.D.
The department of Physiology welcomes Massimo Scanziani, Ph.D.
The department of Physiology welcomes Peter Strickland, Ph.D.
The department of Physiology welcomes Denise Cai, Ph.D.
Focus of Work: My research focuses on the basal ganglia, a group of subcortical brain nuclei that are critical for voluntary movement and associative learning and are the primary sites of dysfunction in Parkinson s disease, Huntington s disease, obsessive-compulsive disorder and addiction.
The department of Physiology welcomes Zachary Knight, Ph.D.